A teenager has been killed and more than 200 Palestinians injured as clashes with Israeli forces and settlers continued in the occupied West Bank.
The violence followed Israel's decision to bar Palestinians from accessing Jerusalem's Old City unless they were residents, a move Hamas called "racist and illegal".
Israeli forces used live ammunition and rubber-coated steel bullets against Palestinian protesters during Sunday's clashes, the Palestinian Red Crescent Society (PRCS) said.
Huthaifa Suleiman, an 18-year-old Palestinian who was shot by Israeli forces during clashes at the Tulkarm checkpoint for throwing fire bombs, later died of his wounds.
The PRCS said almost 400 people have been injured, including 150 suffering from bullet wounds.
More than 200 have been treated for the effects of tear gas, it said.
Clashes took place in areas including Jenin in the occupied West Bank and the East Jerusalem neighborhood of Issawiya.
The PRCS has declared a state of emergency in the West Bank and East Jerusalem in response to what it said were "attacks by occupation forces and settlers".
Ambulances operated by the organization were attacked by Israeli soldiers on Friday and Sunday, and five of its paramedics have been assaulted by troops, the PRCS said in a statement released on its website on Sunday.
"[The] PRCS underlines that these practices constitute a blatant violation of key IHL [international humanitarian law] provisions, mainly the Fourth Geneva Convention of 1949 on the protection of civilians in time of war," the statement read.
Meanwhile, Israeli local media reported that a 30-year-old Israeli was stabbed by two masked men in the southern Israeli port and resort town of Eilat early on Monday.
The Israeli army also said in a statement that rockets fired from the besieged Gaza Strip had hit southern Israel, with no injuries reported.
Israel said it had launched an air strike targeting northern Gaza in response.
'Sharpen our measures'
The violence has raised fears of further military action by Israel.
Prime Minister Benjamin Netanyahu held consultations with his security chiefs on Sunday, and his security cabinet is also to meet on Monday.
Israeli Intelligence Minister Israel Katz threatened to launch new military operations against Palestinians, telling Israel's military broadcaster the country would "sharpen" the measures it took.
Israel has banned West Bank Palestinians from entering Jerusalem's Old City for the next two days.
The restrictions on the Old City in the occupied East Jerusalem only allow access to Israelis, tourists, residents of the area, business owners, and students, police said.
Worship at the sensitive al-Aqsa Mosque compound will be restricted to Old City residents and Palestinian Israelis, and limited to men aged 50 and above.
The latest violence comes amid high tensions in Jerusalem after clashes between police and Palestinians at the compound - Islam's third holiest site.
PHOTO CAPTION
A Palestinian uses a sling shot against Israeli army soldiers during clashes in the occupied West Bank city of Hebron October 4, 2015.
Al-Jazeera