Thousands of Muslims have taken part in a protest in
The crowds booed - and shouted slogans such as "Don't come Pope" - as pictures of Benedict XVI were shown on a giant screen in a square in the city suburbs.
The Pope sparked outrage across the Muslim world in September, when he quoted a 14th-Century Christian emperor who criticized the Prophet Muhammad.
His visit, which begins on Tuesday, will be his first to a Muslim country.
Sunday's protest was organized by the Islamic Felicity Party, a small group that is not represented in the Turkish parliament.
A huge poster on the square showed pictures of a crusader and of violence in the
"Who brought evil and inhumanity?" the poster asked, addressing the Pope. "Now don't come here, unless you apologize."
Police said more than 25,000 protesters had joined the demonstration, which was monitored by hundreds of security officers, including riot police.
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Speaking at a news conference, Turkish Foreign Minister Abdullah Gul tried to play down the controversy.
"We hope this visit will help eliminate misunderstandings between Muslims and Christians," Mr Gul said. "The Pope's message will be very important."
Before the protests, a senior Felicity Party official, Osman Yumakogullari, told AFP news agency: "We have infinite respect for all religions and their representatives, but we cannot remain silent in the face of declarations that go against our faith."
In his September speech, the Pope quoted Emperor Manuel II Paleologos of the
The Pope stressed that these were not his own words and later expressed regret for any offence his words caused.
However many Muslim leaders have been demanding an unequivocal apology.
Photo caption
Posters against Pope Benedict XVI